Intergenerational epigenetic inheritance
نویسندگان
چکیده
منابع مشابه
Mechanisms of epigenetic inheritance.
The mechanisms by which stable gene expression patterns are inherited during cell division are not well understood. Chromatin is subject to a number of covalent modifications and it is generally believed that the transfer of these modifications between cell generations plays a critical role in inheritance, though how this occurs is a matter of debate. In one proposed model, replication of chrom...
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Recent fi ndings in the emerging fi eld of transgenerational epigenetic inheritance suggest that the lifestyle choices and experiences of an individual have biological implications for offspring not yet conceived. Studies show that diet, drugs, and even social experiences can lead to life-long changes in gene expression. Some changes in gene expression are passed down to future generations. The...
متن کاملTransgenerational epigenetic inheritance
Marisa Bartolomei University of Pennsylvania, USA Stefan Beck University College London, UK Christoph Bock University of Vienna, AT Liran Carmel Hebrew University of Jerusalem, IL Katharina Gapp Sanger Institute, Cambridge, UK Johannes Graeff Ecole Polytechnique Fédérale, Lausanne, CH Carlos Guerrero-Bosagna Linköping University, SE Eva Jablonka Tel Aviv University, IL Josep Chillarón Hospital ...
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Centromeres of higher eukaryotes are epigenetically maintained; however, the mechanism that underlies centromere inheritance is unknown. Centromere identity and inheritance require the assembly of nucleosomes containing the CenH3 histone variant in place of canonical H3. Work from our laboratory has led to the proposal that epigenetic inheritance of centromeres evolved as adaptations of CenH3 a...
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his chapter is about material transfers among adult family generations. They occur either as inter vivos gifts or as bequests. These two types have often been analyzed separately despite good reasons to treat them together. The description and explanation of such transfers has been the subject of a broad range of theoretical approaches, including sociological theories of the social antecedents ...
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ژورنال
عنوان ژورنال: Nature Genetics
سال: 2014
ISSN: 1061-4036,1546-1718
DOI: 10.1038/ng.3054